Cargando…

Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation

Nuclear factor erythroid-derived 2 (NF-E2) has been associated with megakaryocyte maturation and platelet production. Recently, an increased in NF-E2 activity has been implicated in myeloproliferative neoplasms. Here, we investigate the role of NF-E2 in normal human hematopoiesis. Knockdown of NF-E2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Di Tullio, Alessandro, Passaro, Diana, Rouault-Pierre, Kevin, Purewal, Sukhveer, Bonnet, Dominique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511106/ https://www.ncbi.nlm.nih.gov/pubmed/28648895 http://dx.doi.org/10.1016/j.stemcr.2017.05.027

Ejemplares similares

IL-12 supports in vitro self-renewal of LT HSC
Publicado: (2022)

Bmi-1 Regulates Extensive Erythroid Self-Renewal
por: Kim, Ah Ram, et al.
Publicado: (2015)

Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches
por: Abarrategi, Ander, et al.
Publicado: (2018)

Notch Signaling in HSC Emergence: When, Why and How
por: Thambyrajah, Roshana, et al.
Publicado: (2022)

Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia
por: Passaro, Diana, et al.
Publicado: (2017)

PPARα and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal
por: Lee, Hsiang-Ying, et al.
Publicado: (2015)

UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal
por: Chagraoui, Jalila, et al.
Publicado: (2019)

Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy
por: Chen, Ran, et al.
Publicado: (2021)

Zfp36l2 is required for self-renewal of early erythroid BFU-E progenitors
por: Zhang, Lingbo, et al.
Publicado: (2013)

The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia
por: Di Tullio, Alessandro, et al.
Publicado: (2017)

Constitutive Activation of STAT5A Promotes Human Hematopoietic Stem Cell Self-Renewal and Erythroid Differentiation
por: Schuringa, Jan Jacob, et al.
Publicado: (2004)

SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells
por: Gerby, Bastien, et al.
Publicado: (2014)

Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma
por: Kahn, Suzana A., et al.
Publicado: (2018)

The Key Role of MicroRNAs in Self-Renewal and Differentiation of Embryonic Stem Cells
por: Divisato, Giuseppina, et al.
Publicado: (2020)

Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal
por: Aguirre, Adan, et al.
Publicado: (2010)

Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis
por: Uhrigshardt, Helge, et al.
Publicado: (2013)

Prep1 (pKnox1) Regulates Mouse Embryonic HSC Cycling and Self-Renewal Affecting the Stat1-Sca1 IFN-Dependent Pathway
por: Modica, Livia, et al.
Publicado: (2014)

Publisher Correction: Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma
por: Kahn, Suzana A., et al.
Publicado: (2018)

FLI-06 Intercepts Notch Signaling And Suppresses The Proliferation And Self-renewal Of Tongue Cancer Cells
por: Gan, Rui-huan, et al.
Publicado: (2019)

Nuclear RNA Sequencing of the Mouse Erythroid Cell Transcriptome
por: Mitchell, Jennifer A., et al.
Publicado: (2012)

Hsc70’s trip to the tip
por: Leslie, Mitch
Publicado: (2015)

Thrombopoietin: tickling the HSC's fancy
por: Kim, Ah Ram, et al.
Publicado: (2017)

Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation
por: Tao, Zhennan, et al.
Publicado: (2018)

A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self‐renewal
por: Chen, Kai‐Yuan, et al.
Publicado: (2017)

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells
por: Rajakulendran, Nishani, et al.
Publicado: (2019)

Hypoxia Regulates the Self-Renewal of Endometrial Mesenchymal Stromal/Stem-like Cells via Notch Signaling
por: Zhang, Sisi, et al.
Publicado: (2022)

Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly
por: Xing, Yi, et al.
Publicado: (2010)

Awakening the HSC: Dynamic Modeling of HSC Maintenance Unravels Regulation of the TP53 Pathway and Quiescence
por: Ikonomi, Nensi, et al.
Publicado: (2020)

Mast Cell Repopulating Ability Is Lost During the Transition From Pre-HSC to FL HSC
por: Yoshimoto, Momoko, et al.
Publicado: (2022)

Comparative analysis of the anticoagulant activities and immunogenicity of HSC70 and HSC70(TKD) of Haemaphysalis flava
por: Liu, Yu-Ke, et al.
Publicado: (2022)

Disruption of erythroid nuclear opening and histone release in myelodysplastic syndromes
por: Zhao, Baobing, et al.
Publicado: (2019)

Regulation of stem cell self-renewal and differentiation by Wnt and Notch are conserved throughout the adenoma-carcinoma sequence in the colon
por: Prasetyanti, Pramudita Ramadhina, et al.
Publicado: (2013)

Notch3 functions as a regulator of cell self-renewal by interacting with the β-catenin pathway in hepatocellular carcinoma
por: Zhang, Qingyu, et al.
Publicado: (2015)

The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma
por: Ignatius, Myron S., et al.
Publicado: (2017)

p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs
por: Choi, Hye Yeon, et al.
Publicado: (2020)

Different Motile Behaviors of Human Hematopoietic Stem versus Progenitor Cells at the Osteoblastic Niche
por: Foster, Katie, et al.
Publicado: (2015)

Filgrastim-Associated Pneumonitis in Cancer Patient Undergoing Hematopoietic Stem Cell (HSC) Mobilization for Autologous-HSC Transplantation
por: Patel, Drashti R, et al.
Publicado: (2020)

Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation
por: Chen, Ji-Lin, et al.
Publicado: (2017)

Expression of Nuclear Factor Erythroid 2 Protein in Malignant Cutaneous Tumors
por: Choi, Chang Yong, et al.
Publicado: (2014)

The bHLH Repressor Deadpan Regulates the Self-renewal and Specification of Drosophila Larval Neural Stem Cells Independently of Notch
por: Zhu, Sijun, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_gjibkbgfg5g92d5p32i7suttq6