Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate

Notch signaling plays a role in specifying a cardiac fate but the downstream effectors remain unknown. In this study we implicate the Notch downstream effector HES5 in cardiogenesis. We show transient Hes5 expression in early mesoderm of gastrulating embryos and demonstrate, by loss and gain-of-func...

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Detalles Bibliográficos
Autores principales: Freire, Ana G., Waghray, Avinash, Soares-da-Silva, Francisca, Resende, Tatiana P., Lee, Dung-Fang, Pereira, Carlos-Filipe, Nascimento, Diana S., Lemischka, Ihor R., Pinto-do-Ó, Perpétua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511108/
https://www.ncbi.nlm.nih.gov/pubmed/28648899
http://dx.doi.org/10.1016/j.stemcr.2017.05.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511108/
https://www.ncbi.nlm.nih.gov/pubmed/28648899
http://dx.doi.org/10.1016/j.stemcr.2017.05.025

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