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Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate
Notch signaling plays a role in specifying a cardiac fate but the downstream effectors remain unknown. In this study we implicate the Notch downstream effector HES5 in cardiogenesis. We show transient Hes5 expression in early mesoderm of gastrulating embryos and demonstrate, by loss and gain-of-func...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511108/ https://www.ncbi.nlm.nih.gov/pubmed/28648899 http://dx.doi.org/10.1016/j.stemcr.2017.05.025 |