Cargando…

NODAL Secures Pluripotency upon Embryonic Stem Cell Progression from the Ground State

Naive mouse embryonic stem cells (ESCs) can develop multiple fates, but the cellular and molecular processes that enable lineage competence are poorly characterized. Here, we investigated progression from the ESC ground state in defined culture. We utilized downregulation of Rex1::GFPd2 to track the...

Descripción completa

Detalles Bibliográficos
Autores principales: Mulas, Carla, Kalkan, Tüzer, Smith, Austin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511111/
https://www.ncbi.nlm.nih.gov/pubmed/28669603
http://dx.doi.org/10.1016/j.stemcr.2017.05.033