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The adipokine leptin modulates adventitial pericyte functions by autocrine and paracrine signalling

Transplantation of adventitial pericytes (APCs) improves recovery from tissue ischemia in preclinical animal models by still unknown mechanisms. This study investigates the role of the adipokine leptin (LEP) in the regulation of human APC biological functions. Transcriptomic analysis of APCs showed...

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Detalles Bibliográficos
Autores principales: Riu, Federica, Slater, Sadie C., Garcia, Eva Jover, Rodriguez-Arabaolaza, Iker, Alvino, Valeria, Avolio, Elisa, Mangialardi, Giuseppe, Cordaro, Andrea, Satchell, Simon, Zebele, Carlo, Caporali, Andrea, Angelini, Gianni, Madeddu, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511138/
https://www.ncbi.nlm.nih.gov/pubmed/28710369
http://dx.doi.org/10.1038/s41598-017-05868-y