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The adipokine leptin modulates adventitial pericyte functions by autocrine and paracrine signalling
Transplantation of adventitial pericytes (APCs) improves recovery from tissue ischemia in preclinical animal models by still unknown mechanisms. This study investigates the role of the adipokine leptin (LEP) in the regulation of human APC biological functions. Transcriptomic analysis of APCs showed...
Autores principales: | Riu, Federica, Slater, Sadie C., Garcia, Eva Jover, Rodriguez-Arabaolaza, Iker, Alvino, Valeria, Avolio, Elisa, Mangialardi, Giuseppe, Cordaro, Andrea, Satchell, Simon, Zebele, Carlo, Caporali, Andrea, Angelini, Gianni, Madeddu, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511138/ https://www.ncbi.nlm.nih.gov/pubmed/28710369 http://dx.doi.org/10.1038/s41598-017-05868-y |
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