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Ageing and latent CMV infection impact on maturation, differentiation and exhaustion profiles of T-cell receptor gammadelta T-cells

Ageing is a broad cellular process, largely affecting the immune system, especially T-lymphocytes. Additionally to immunosenescence alone, cytomegalovirus (CMV) infection is thought to have major impacts on T-cell subset composition and exhaustion. These impacts have been studied extensively in TCRα...

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Detalles Bibliográficos
Autores principales: Kallemeijn, Martine J., Boots, Anne Mieke H., van der Klift, Michèle Y., Brouwer, Elisabeth, Abdulahad, Wayel H., Verhaar, Jan A. N., van Dongen, Jacques J. M., Langerak, Anton W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511140/
https://www.ncbi.nlm.nih.gov/pubmed/28710491
http://dx.doi.org/10.1038/s41598-017-05849-1