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Ageing and latent CMV infection impact on maturation, differentiation and exhaustion profiles of T-cell receptor gammadelta T-cells
Ageing is a broad cellular process, largely affecting the immune system, especially T-lymphocytes. Additionally to immunosenescence alone, cytomegalovirus (CMV) infection is thought to have major impacts on T-cell subset composition and exhaustion. These impacts have been studied extensively in TCRα...
Autores principales: | Kallemeijn, Martine J., Boots, Anne Mieke H., van der Klift, Michèle Y., Brouwer, Elisabeth, Abdulahad, Wayel H., Verhaar, Jan A. N., van Dongen, Jacques J. M., Langerak, Anton W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511140/ https://www.ncbi.nlm.nih.gov/pubmed/28710491 http://dx.doi.org/10.1038/s41598-017-05849-1 |
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