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RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity

Mitochondria act as a platform for antiviral innate immunity, and the immune system depends on activation of the retinoic acid-inducible gene I (RIG-I)-like receptors (RLR) signaling pathway via an adaptor molecule, mitochondrial antiviral signaling. We report that RLR-mediated antiviral innate immu...

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Detalles Bibliográficos
Autores principales: Yoshizumi, Takuma, Imamura, Hiromi, Taku, Tomohiro, Kuroki, Takahiro, Kawaguchi, Atsushi, Ishikawa, Kaori, Nakada, Kazuto, Koshiba, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511143/
https://www.ncbi.nlm.nih.gov/pubmed/28710430
http://dx.doi.org/10.1038/s41598-017-05808-w