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Deviation of the typical AAA substrate-threading pore prevents fatal protein degradation in yeast Cdc48
Yeast Cdc48 is a well-conserved, essential chaperone of ATPases associated with diverse cellular activity (AAA) proteins, which recognizes substrate proteins and modulates their conformations to carry out many cellular processes. However, the fundamental mechanisms underlying the diverse pivotal rol...
Autores principales: | Esaki, Masatoshi, Islam, Md. Tanvir, Tani, Naoki, Ogura, Teru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511170/ https://www.ncbi.nlm.nih.gov/pubmed/28710470 http://dx.doi.org/10.1038/s41598-017-05806-y |
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