Conformational Transitions of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor, a Human Class B GPCR

The G protein-coupled pituitary adenylate cyclase-activating polypeptide receptor (PAC1R) is a potential therapeutic target for endocrine, metabolic and stress-related disorders. However, many questions regarding the protein structure and dynamics of PAC1R remain largely unanswered. Using microsecon...

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Detalles Bibliográficos
Autores principales: Liao, Chenyi, Zhao, Xiaochuan, Brewer, Matthias, May, Victor, Li, Jianing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511175/
https://www.ncbi.nlm.nih.gov/pubmed/28710390
http://dx.doi.org/10.1038/s41598-017-05815-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511175/
https://www.ncbi.nlm.nih.gov/pubmed/28710390
http://dx.doi.org/10.1038/s41598-017-05815-x

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