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Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling

The metabolic processes of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)] into PI(3,4,5)P(3) and the subsequent PI(3,4,5)P(3) signalling are involved in cell migration. Dysfunctions in the control of this pathway can cause human cancer cell migration and metastatic growth. Here we investigated...

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Detalles Bibliográficos
Autores principales: Asano, Satoshi, Taniguchi, Yuri, Yamawaki, Yosuke, Gao, Jing, Harada, Kae, Takeuchi, Hiroshi, Hirata, Masato, Kanematsu, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511194/
https://www.ncbi.nlm.nih.gov/pubmed/28710365
http://dx.doi.org/10.1038/s41598-017-05908-7