The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells

Mutations in the tumor suppressor p53 are among the most highly occurring events in colorectal cancer (CRC). Such mutations have been shown to influence the sensitivity of cancer cells to chemotherapeutic agents. However their impact on the efficacy of the proteasomal inhibitor bortezomib remains co...

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Detalles Bibliográficos
Autores principales: Dabiri, Yasamin, Kalman, Sara, Gürth, Clara-Marie, Kim, Jee Young, Mayer, Viola, Cheng, Xinlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511205/
https://www.ncbi.nlm.nih.gov/pubmed/28710427
http://dx.doi.org/10.1038/s41598-017-05813-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511205/
https://www.ncbi.nlm.nih.gov/pubmed/28710427
http://dx.doi.org/10.1038/s41598-017-05813-z

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