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Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder
Metabolic and functional alterations of neurons in the dorsolateral prefrontal cortex (dlPFC) are thought to contribute to impulsivity, which is a hallmark of addictive behaviors that underlie compulsive drug seeking and taking in humans. To determine if there is a transcriptional signature in dlPFC...
Autores principales: | Ribeiro, Efrain A., Scarpa, Joseph R., Garamszegi, Susanna P., Kasarskis, Andrew, Mash, Deborah C., Nestler, Eric J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511210/ https://www.ncbi.nlm.nih.gov/pubmed/28710498 http://dx.doi.org/10.1038/s41598-017-05720-3 |
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