TALEN based HPV-E7 editing triggers necrotic cell death in cervical cancer cells

Human Papillomavirus E7 and E6 oncoproteins have been considered as suitable candidate anti-viral targets since they cause malignant conversion in cervical cancers. Transcription Activator-Like Effector Nucleases (TALENs) are recent editing tools to knockout genes by inducing double stranded breaks...

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Detalles Bibliográficos
Autores principales: Shankar, Sumitra, Prasad, Deepti, Sanawar, Rahul, Das, Ani V., Pillai, M. Radhakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511212/
https://www.ncbi.nlm.nih.gov/pubmed/28710417
http://dx.doi.org/10.1038/s41598-017-05696-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511212/
https://www.ncbi.nlm.nih.gov/pubmed/28710417
http://dx.doi.org/10.1038/s41598-017-05696-0

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