Protein Tyrosine Phosphatase Inhibition Prevents Experimental Cerebral Malaria by Precluding CXCR3 Expression on T Cells

Cerebral malaria induced by Plasmodium berghei ANKA infection is dependent on the sequestration of cytotoxic T cells within the brain and augmentation of the inflammatory response. Herein, we demonstrate that inhibition of protein tyrosine phosphatase (PTP) activity significantly attenuates T cell s...

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Detalles Bibliográficos
Autores principales: Van Den Ham, Kristin M., Smith, Logan K., Richer, Martin J., Olivier, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511231/
https://www.ncbi.nlm.nih.gov/pubmed/28710387
http://dx.doi.org/10.1038/s41598-017-05609-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511231/
https://www.ncbi.nlm.nih.gov/pubmed/28710387
http://dx.doi.org/10.1038/s41598-017-05609-1

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