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Phthalide Derivatives from Angelica Sinensis Decrease Hemoglobin Oxygen Affinity: A New Allosteric-Modulating Mechanism and Potential Use as 2,3-BPG Functional Substitutes

Angelica sinensis (AS), one of the most versatile herbal medicines remains widely used due to its multi-faceted pharmacologic activities. Besides its traditional use as the blood-nourishing tonic, its anti-hypertensive, anti-cardiovascular, neuroprotective and anti-cancer effects have been reported....

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Detalles Bibliográficos
Autores principales: Chen, Wei-Ren, Yu, Youqing, Zulfajri, Muhammad, Lin, Ping-Cheng, Wang, Chia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511246/
https://www.ncbi.nlm.nih.gov/pubmed/28710372
http://dx.doi.org/10.1038/s41598-017-04554-3