Kinetic insights into the temperature dependence of DNA strand cleavage and religation by topoisomerase III from the hyperthermophile Sulfolobus solfataricus

All cellular organisms encode type IA topoisomerases which catalyze DNA topological changes essential for DNA transactions. However, the kinetics of the reaction catalyzed by these enzymes remains poorly characterized. Here we measured the rapid kinetics of template binding, cleavage and religation...

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Detalles Bibliográficos
Autores principales: Zhang, Junhua, Pan, Bailong, Li, Zhimeng, Sheng Zhao, Xin, Huang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511271/
https://www.ncbi.nlm.nih.gov/pubmed/28710489
http://dx.doi.org/10.1038/s41598-017-05837-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511271/
https://www.ncbi.nlm.nih.gov/pubmed/28710489
http://dx.doi.org/10.1038/s41598-017-05837-5

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