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Exosomes derived from pancreatic cancer cells induce insulin resistance in C2C12 myotube cells through the PI3K/Akt/FoxO1 pathway

Prospective epidemiological studies have consistently suggested that pancreatic cancer-associated new-onset diabetes mellitus (PC-DM) represents a potential platform for early diagnose of pancreatic cancer (PC). Despite the studies performed, the mechanism behind this phenomenon remains ambiguous. I...

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Detalles Bibliográficos
Autores principales: Wang, Lantian, Zhang, Bo, Zheng, Wen, Kang, Muxing, Chen, Qing, Qin, Wenjie, Li, Chao, Zhang, Yuefeng, Shao, Yingkuan, Wu, Yulian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511275/
https://www.ncbi.nlm.nih.gov/pubmed/28710412
http://dx.doi.org/10.1038/s41598-017-05541-4