Ssu72 attenuates autoimmune arthritis via targeting of STAT3 signaling and Th17 activation

Signal transducer and activator of transcription 3 (STAT3) orchestrates the differentiation of several cell types, including interleukin-17 (IL-17)-releasing Th17 cells. Dysregulation of Th17 cells results in chronic inflammatory responses. Ssu72 is a C-terminal domain phosphatase required for trans...

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Detalles Bibliográficos
Autores principales: Lee, Seung Hoon, Kim, Eun-Kyung, Kwon, Jeong-Eun, Lee, Jin-Kwan, Lee, DoHyeong, Kim, Se-Young, Seo, Hyeon-Beom, Na, Hyun Sik, Jung, KyoungAh, Kwok, Seung-Ki, Lee, Chang-Woo, Park, Sung-Hwan, Cho, Mi-La
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511296/
https://www.ncbi.nlm.nih.gov/pubmed/28710354
http://dx.doi.org/10.1038/s41598-017-05421-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511296/
https://www.ncbi.nlm.nih.gov/pubmed/28710354
http://dx.doi.org/10.1038/s41598-017-05421-x

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