Sildenafil, a Phosphodiesterase Type 5 Inhibitor, Downregulates Osteopontin in Human Peripheral Blood Mononuclear Cells

The aim of this study was to investigate the ability of sildenafil to regulate osteopontin (OPN) gene and protein in peripheral blood mononuclear cells (PBMCs) from healthy blood donors. OPN is expressed by a wide variety of cell types, including immune cells. OPN functions are linked to various phy...

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Detalles Bibliográficos
Autores principales: Kaleta, Beata, Boguska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511304/
https://www.ncbi.nlm.nih.gov/pubmed/28210757
http://dx.doi.org/10.1007/s00005-017-0455-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511304/
https://www.ncbi.nlm.nih.gov/pubmed/28210757
http://dx.doi.org/10.1007/s00005-017-0455-9

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