Inhibition of CTGF ameliorates peritoneal fibrosis through suppression of fibroblast and myofibroblast accumulation and angiogenesis

Peritoneal fibrosis (PF) is a serious complication in various clinical settings, but the mechanisms driving it remain to be fully determined. Connective tissue growth factor (CTGF) is known to regulate fibroblast activities. We therefore examined if CTGF inhibition has anti-fibrotic effects in PF. P...

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Detalles Bibliográficos
Autores principales: Sakai, Norihiko, Nakamura, Miki, Lipson, Kenneth E., Miyake, Taito, Kamikawa, Yasutaka, Sagara, Akihiro, Shinozaki, Yasuyuki, Kitajima, Shinji, Toyama, Tadashi, Hara, Akinori, Iwata, Yasunori, Shimizu, Miho, Furuichi, Kengo, Kaneko, Shuichi, Tager, Andrew M., Wada, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511333/
https://www.ncbi.nlm.nih.gov/pubmed/28710437
http://dx.doi.org/10.1038/s41598-017-05624-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511333/
https://www.ncbi.nlm.nih.gov/pubmed/28710437
http://dx.doi.org/10.1038/s41598-017-05624-2

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