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Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in the Developing Mouse Cochlea

Although STAT3 signaling is demonstrated to regulate sensory cell differentiation and regeneration in the zebrafish, its exact role is still unclear in mammalian cochleae. Here, we report that STAT3 and its activated form are specifically expressed in hair cells during mouse cochlear development. Im...

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Detalles Bibliográficos
Autores principales: Chen, Qianqian, Quan, Yizhou, Wang, Naitao, Xie, Chengying, Ji, Zhongzhong, He, Hao, Chai, Renjie, Li, Huawei, Yin, Shankai, Chin, Y. Eugene, Wei, Xunbin, Gao, Wei-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511372/
https://www.ncbi.nlm.nih.gov/pubmed/28669599
http://dx.doi.org/10.1016/j.stemcr.2017.05.031