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Anti-fibrotic Effects of Synthetic Oligodeoxynucleotide for TGF-β1 and Smad in an Animal Model of Liver Cirrhosis

Liver fibrosis is characterized by changes in tissue architecture and extracellular matrix composition. Liver fibrosis affects not only hepatocytes but also the non-parenchymal cells such as hepatic stellate cells (HSCs), which are essential for maintaining an intact liver structure and function. Tr...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Yeon, An, Hyun-Jin, Kim, Woon-Hae, Gwon, Mi-Gyeong, Gu, Hyemin, Park, Yoon-Yub, Park, Kwan-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511593/
https://www.ncbi.nlm.nih.gov/pubmed/28918026
http://dx.doi.org/10.1016/j.omtn.2017.06.022