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Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine

Dexmedetomidine is an α(2)-adrenoceptor agonist with sedative, anxiolytic, sympatholytic, and analgesic-sparing effects, and minimal depression of respiratory function. It is potent and highly selective for α(2)-receptors with an α(2):α(1) ratio of 1620:1. Hemodynamic effects, which include transien...

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Detalles Bibliográficos
Autores principales: Weerink, Maud A. S., Struys, Michel M. R. F., Hannivoort, Laura N., Barends, Clemens R. M., Absalom, Anthony R., Colin, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511603/
https://www.ncbi.nlm.nih.gov/pubmed/28105598
http://dx.doi.org/10.1007/s40262-017-0507-7