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Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine
Dexmedetomidine is an α(2)-adrenoceptor agonist with sedative, anxiolytic, sympatholytic, and analgesic-sparing effects, and minimal depression of respiratory function. It is potent and highly selective for α(2)-receptors with an α(2):α(1) ratio of 1620:1. Hemodynamic effects, which include transien...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511603/ https://www.ncbi.nlm.nih.gov/pubmed/28105598 http://dx.doi.org/10.1007/s40262-017-0507-7 |