Cargando…

Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine

Dexmedetomidine is an α(2)-adrenoceptor agonist with sedative, anxiolytic, sympatholytic, and analgesic-sparing effects, and minimal depression of respiratory function. It is potent and highly selective for α(2)-receptors with an α(2):α(1) ratio of 1620:1. Hemodynamic effects, which include transien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weerink, Maud A. S., Struys, Michel M. R. F., Hannivoort, Laura N., Barends, Clemens R. M., Absalom, Anthony R., Colin, Pieter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2017
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511603/ https://www.ncbi.nlm.nih.gov/pubmed/28105598 http://dx.doi.org/10.1007/s40262-017-0507-7

Ejemplares similares

Comment on Morse et al. A Universal Pharmacokinetic Model for Dexmedetomidine in Children and Adults. J. Clin. Med. 2020, 9, 3480
por: Eleveld, Douglas J., et al.
Publicado: (2021)

Clinical Pharmacokinetics and Pharmacodynamics of Propofol
por: Sahinovic, Marko M., et al.
Publicado: (2018)

General Purpose Pharmacokinetic-Pharmacodynamic Models for Target-Controlled Infusion of Anaesthetic Drugs: A Narrative Review
por: Vandemoortele, Ophélie, et al.
Publicado: (2022)

Dexmedetomidine-induced deep sedation mimics non-rapid eye movement stage 3 sleep: large-scale validation using machine learning
por: Ramaswamy, Sowmya M, et al.
Publicado: (2020)

Etomidate and its Analogs: A Review of Pharmacokinetics and Pharmacodynamics
por: Valk, Beatrijs I., et al.
Publicado: (2021)

Dexmedetomidine versus Midazolam in Procedural Sedation. A Systematic Review of Efficacy and Safety
por: Barends, Clemens R. M., et al.
Publicado: (2017)

What’s New in Intravenous Anaesthesia? New Hypnotics, New Models and New Applications
por: Vellinga, Remco, et al.
Publicado: (2022)

Predicting Deep Hypnotic State From Sleep Brain Rhythms Using Deep Learning: A Data-Repurposing Approach
por: Belur Nagaraj, Sunil, et al.
Publicado: (2020)

Population Pharmacokinetics and Pharmacodynamics of Dexmedetomidine in Children Undergoing Ambulatory Surgery
por: Pérez-Guillé, María-Gabriela, et al.
Publicado: (2018)

Intranasal midazolam for the sedation of geriatric patients with care‐resistant behaviour during essential dental treatment: An observational study
por: Barends, Clemens R. M., et al.
Publicado: (2021)

Clinical Pharmacokinetics and Pharmacodynamics of Dalcetrapib
por: Black, Donald M., et al.
Publicado: (2018)

Clinical Pharmacokinetics and Pharmacodynamics of Micafungin
por: Wasmann, Roeland E., et al.
Publicado: (2017)

Clinical Pharmacokinetics and Pharmacodynamics of Immune Checkpoint Inhibitors
por: Centanni, Maddalena, et al.
Publicado: (2019)

BIS and spectral entropy monitoring during sedation with midazolam/remifentanil and dexmedetomidine/remifentanil
por: Absalom, Anthony R, et al.
Publicado: (2009)

Clinical Pharmacokinetics and Pharmacodynamics of Lenalidomide
por: Chen, Nianhang, et al.
Publicado: (2016)

Clinical Pharmacokinetics and Pharmacodynamics of Nintedanib
por: Wind, Sven, et al.
Publicado: (2019)

Clinical Pharmacokinetics and Pharmacodynamics of Afatinib
por: Wind, Sven, et al.
Publicado: (2016)

Clinical Pharmacokinetics and Pharmacodynamics of Cefiderocol
por: Bilal, Muhammad, et al.
Publicado: (2021)

Clinical Pharmacokinetics and Pharmacodynamics of Roxadustat
por: Czock, David, et al.
Publicado: (2021)

Clinical Pharmacokinetics and Pharmacodynamics of Desmoteplase
por: Piechowski-Jozwiak, Bartlomiej, et al.
Publicado: (2021)

Clinical Pharmacokinetics and Pharmacodynamics of Rucaparib
por: Liao, Mingxiang, et al.
Publicado: (2022)

Clinical Pharmacokinetics and Pharmacodynamics of Voclosporin
por: Abdel-Kahaar, Emaad, et al.
Publicado: (2023)

Pharmacokinetics and Pharmacodynamics of Butorphanol and Dexmedetomidine after Intranasal Administration in Broiler Chickens (Gallus gallus domesticus)
por: Sha, Jin, et al.
Publicado: (2022)

Hypotension during propofol sedation for colonoscopy: a retrospective exploratory analysis and meta-analysis
por: Sneyd, J. Robert, et al.
Publicado: (2022)

Clinical Pharmacokinetics and Pharmacodynamics of Pazopanib: Towards Optimized Dosing
por: Verheijen, Remy B., et al.
Publicado: (2017)

Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions
por: Anderson, Lyndsey L., et al.
Publicado: (2019)

Pharmacokinetics and Pharmacodynamics of Posaconazole
por: Chen, Lu, et al.
Publicado: (2020)

Clinical Pharmacokinetic and Pharmacodynamic Profile of Riociguat
por: Frey, Reiner, et al.
Publicado: (2017)

Clinical Pharmacokinetic and Pharmacodynamic Profile of Rivaroxaban
por: Mueck, Wolfgang, et al.
Publicado: (2013)

Clinical Pharmacokinetics and Pharmacodynamics of CSL112
por: Ortega-Paz, Luis, et al.
Publicado: (2023)

Clinical Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Anifrolumab
por: Tang, Weifeng, et al.
Publicado: (2023)

Clinical Pharmacokinetic and Pharmacodynamic Considerations in the Treatment of Ulcerative Colitis
por: Berends, Sophie E., et al.
Publicado: (2018)

Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen
por: de Vries Schultink, Aurelia H. M., et al.
Publicado: (2015)

Pharmacokinetics and Pharmacodynamics of Ibrexafungerp
por: McCarthy, Matthew William
Publicado: (2021)

Pharmacokinetics and Pharmacodynamics of Tedizolid
por: Iqbal, Khalid, et al.
Publicado: (2022)

Isavuconazole Pharmacokinetics and Pharmacodynamics in Children
por: Elhence, Hirsh, et al.
Publicado: (2022)

Proteasome Inhibitors and Their Pharmacokinetics, Pharmacodynamics, and Metabolism
por: Wang, Jinhai, et al.
Publicado: (2021)

Comparison of haemodynamic- and electroencephalographic-monitored effects evoked by four combinations of effect-site concentrations of propofol and remifentanil, yielding a predicted tolerance to laryngoscopy of 90%
por: van den Berg, J. P., et al.
Publicado: (2020)

Population Pharmacodynamic Modeling Using the Sigmoid E(max) Model: Influence of Inter-individual Variability on the Steepness of the Concentration–Effect Relationship. a Simulation Study
por: Proost, Johannes H., et al.
Publicado: (2020)

Clinical Pharmacokinetics and Pharmacodynamics of the Endothelin Receptor Antagonist Macitentan
por: Sidharta, P. N., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tk7m0jtn10ma3e19eqg2v4rqt0