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RCAN1.4 regulates VEGFR-2 internalisation, cell polarity and migration in human microvascular endothelial cells

Regulator of calcineurin 1 (RCAN1) is an endogenous inhibitor of the calcineurin pathway in cells. It is expressed as two isoforms in vertebrates: RCAN1.1 is constitutively expressed in most tissues, whereas transcription of RCAN1.4 is induced by several stimuli that activate the calcineurin-NFAT pa...

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Detalles Bibliográficos
Autores principales: Alghanem, Ahmad F., Wilkinson, Emma L., Emmett, Maxine S., Aljasir, Mohammad A., Holmes, Katherine, Rothermel, Beverley A., Simms, Victoria A., Heath, Victoria L., Cross, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511620/
https://www.ncbi.nlm.nih.gov/pubmed/28271280
http://dx.doi.org/10.1007/s10456-017-9542-0