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Automated Image Analysis of HER2 Fluorescence In Situ Hybridization to Refine Definitions of Genetic Heterogeneity in Breast Cancer Tissue

Human epidermal growth factor receptor 2 gene- (HER2-) targeted therapy for breast cancer relies primarily on HER2 overexpression established by immunohistochemistry (IHC) with borderline cases being further tested for amplification by fluorescence in situ hybridization (FISH). Manual interpretation...

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Detalles Bibliográficos
Autores principales: Radziuviene, Gedmante, Rasmusson, Allan, Augulis, Renaldas, Lesciute-Krilaviciene, Daiva, Laurinaviciene, Aida, Clim, Eduard, Laurinavicius, Arvydas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511668/
https://www.ncbi.nlm.nih.gov/pubmed/28752092
http://dx.doi.org/10.1155/2017/2321916