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Automated Image Analysis of HER2 Fluorescence In Situ Hybridization to Refine Definitions of Genetic Heterogeneity in Breast Cancer Tissue
Human epidermal growth factor receptor 2 gene- (HER2-) targeted therapy for breast cancer relies primarily on HER2 overexpression established by immunohistochemistry (IHC) with borderline cases being further tested for amplification by fluorescence in situ hybridization (FISH). Manual interpretation...
Autores principales: | Radziuviene, Gedmante, Rasmusson, Allan, Augulis, Renaldas, Lesciute-Krilaviciene, Daiva, Laurinaviciene, Aida, Clim, Eduard, Laurinavicius, Arvydas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511668/ https://www.ncbi.nlm.nih.gov/pubmed/28752092 http://dx.doi.org/10.1155/2017/2321916 |
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