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Recombinant Immunotoxin Therapy of Glioblastoma: Smart Design, Key Findings, and Specific Challenges

Recombinant immunotoxins (RITs) refer to a group of recombinant protein-based therapeutics, which consists of two components: an antibody variable fragment or a specific ligand that allows RITs to bind specifically to target cells and an engineered toxin fragment that kills the target cells upon int...

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Detalles Bibliográficos
Autores principales: Zhu, Shaowei, Liu, Yuanyi, Wang, Paul C., Gu, Xinbin, Shan, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511670/
https://www.ncbi.nlm.nih.gov/pubmed/28752098
http://dx.doi.org/10.1155/2017/7929286