The Role of BiP Retrieval by the KDEL Receptor in the Early Secretory Pathway and its Effect on Protein Quality Control and Neurodegeneration

Protein quality control in the early secretory pathway is a ubiquitous eukaryotic mechanism for adaptation to endoplasmic reticulum (ER) stress. An ER molecular chaperone, immunoglobulin heavy chain-binding protein (BiP), is one of the essential components in this process. BiP interacts with nascent...

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Detalles Bibliográficos
Autores principales: Jin, Hisayo, Komita, Mari, Aoe, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511815/
https://www.ncbi.nlm.nih.gov/pubmed/28769758
http://dx.doi.org/10.3389/fnmol.2017.00222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511815/
https://www.ncbi.nlm.nih.gov/pubmed/28769758
http://dx.doi.org/10.3389/fnmol.2017.00222

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