Cathepsin S Is Involved in Th17 Differentiation Through the Upregulation of IL-6 by Activating PAR-2 after Systemic Exposure to Lipopolysaccharide from Porphyromonas gingivalis

Positive links have been found between periodontitis and numerous diseases in humans via persistent inflammation throughout the body. However, the main factors responsible for maintaining this pro-inflammatory condition are poorly understood. The spleen, the largest secondary immune organ, is a cent...

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Detalles Bibliográficos
Autores principales: Dekita, Masato, Wu, Zhou, Ni, Junjun, Zhang, Xinwen, Liu, Yicong, Yan, Xu, Nakanishi, Hiroshi, Takahashi, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511830/
https://www.ncbi.nlm.nih.gov/pubmed/28769800
http://dx.doi.org/10.3389/fphar.2017.00470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511830/
https://www.ncbi.nlm.nih.gov/pubmed/28769800
http://dx.doi.org/10.3389/fphar.2017.00470

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