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Pannexins Are Potential New Players in the Regulation of Cerebral Homeostasis during Sleep-Wake Cycle

During brain homeostasis, both neurons and astroglia release ATP that is rapidly converted to adenosine in the extracellular space. Pannexin-1 (Panx1) hemichannels represent a major conduit of non-vesicular ATP release from brain cells. Previous studies have shown that Panx1(−/−) mice possess severe...

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Detalles Bibliográficos
Autores principales: Shestopalov, Valery I., Panchin, Yuri, Tarasova, Olga S., Gaynullina, Dina, Kovalzon, Vladimir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511838/
https://www.ncbi.nlm.nih.gov/pubmed/28769767
http://dx.doi.org/10.3389/fncel.2017.00210