MUC1 O-glycosylation contributes to anoikis resistance in epithelial cancer cells

Anoikis is a fundamental cellular process for maintaining tissue homeostasis. Resistance to anoikis is a hallmark of oncogenic epithelial–mesenchymal transition and is a pre-requisite for metastasis. Previous studies have revealed that the heavily glycosylated mucin protein MUC1, which is overexpres...

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Detalles Bibliográficos
Autores principales: Piyush, Tushar, Rhodes, Jonathan M, Yu, Lu-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511859/
https://www.ncbi.nlm.nih.gov/pubmed/28725490
http://dx.doi.org/10.1038/cddiscovery.2017.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511859/
https://www.ncbi.nlm.nih.gov/pubmed/28725490
http://dx.doi.org/10.1038/cddiscovery.2017.44

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