Cargando…

Rab35 protein regulates evoked exocytosis of endothelial Weibel–Palade bodies

Weibel–Palade bodies (WPB) are secretory organelles of endothelial cells that undergo evoked exocytosis following intracellular Ca(2+) or cAMP elevation, thereby supplying the vasculature with factors controlling hemostasis. Several cytosolic and membrane-associated proteins, including the Rab famil...

Descripción completa

Detalles Bibliográficos
Autores principales: Biesemann, Anja, Gorontzi, Alexandra, Barr, Francis, Gerke, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512060/
https://www.ncbi.nlm.nih.gov/pubmed/28566286
http://dx.doi.org/10.1074/jbc.M116.773333