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Physiological functions and pathogenic potential of uric acid: A review
Uric acid is synthesized mainly in the liver, intestines and the vascular endothelium as the end product of an exogenous pool of purines, and endogenously from damaged, dying and dead cells, whereby nucleic acids, adenine and guanine, are degraded into uric acid. Mentioning uric acid generates dread...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512149/ https://www.ncbi.nlm.nih.gov/pubmed/28748115 http://dx.doi.org/10.1016/j.jare.2017.03.003 |