Antileishmanial activity and tubulin polymerization inhibition of podophyllotoxin derivatives on Leishmania infantum

Leishmania microtubules play an important role not only in cell division, but also in keeping the shape of the parasite and motility of its free-living stages. Microtubules result from the self-assembly of alpha and beta tubulins, two phylogenetically conserved and very abundant eukaryotic proteins...

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Detalles Bibliográficos
Autores principales: Escudero-Martínez, José Miguel, Pérez-Pertejo, Yolanda, Reguera, Rosa M., Castro, María Ángeles, Rojo, María Victoria, Santiago, Carolina, Abad, Andrés, García, Pablo Anselmo, López-Pérez, José Luis, San Feliciano, Arturo, Balaña-Fouce, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512185/
https://www.ncbi.nlm.nih.gov/pubmed/28719882
http://dx.doi.org/10.1016/j.ijpddr.2017.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512185/
https://www.ncbi.nlm.nih.gov/pubmed/28719882
http://dx.doi.org/10.1016/j.ijpddr.2017.06.003

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