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Metabolomics analysis reveals that benzo[a]pyrene, a component of PM(2.5), promotes pulmonary injury by modifying lipid metabolism in a phospholipase A2-dependent manner in vivo and in vitro

Particulate matter with an aerodynamic diameter less than 2.5 μM (PM(2.5)) is one of the major environmental pollutants in China. In this study, we carried out a metabolomics profile study on PM(2.5)-induced inflammation. PM(2.5) from Beijing, China, was collected and given to rats through intra-tra...

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Detalles Bibliográficos
Autores principales: Zhang, Song-Yang, Shao, Danqing, Liu, Huiying, Feng, Juan, Feng, Baihuan, Song, Xiaoming, Zhao, Qian, Chu, Ming, Jiang, Changtao, Huang, Wei, Wang, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512213/
https://www.ncbi.nlm.nih.gov/pubmed/28715731
http://dx.doi.org/10.1016/j.redox.2017.07.001