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Clinically Significant Unclassified Variants in BRCA1 and BRCA2 genes among Korean Breast Cancer Patients

PURPOSE: Unclassified variants (UVs) of BRCA1 and BRCA2 genes are not defined as pathogenic for breast cancer, and their clinical significance currently remains undefined. Therefore, this study was conducted to identify potentially pathogenic UVs by comparing their prevalence between breast cancer p...

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Detalles Bibliográficos
Autores principales: Yoon, Kyong-Ah, Park, Boyoung, Lee, Byung Il, Yang, Moon Jung, Kong, Sun-Young, Lee, Eun Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512368/
https://www.ncbi.nlm.nih.gov/pubmed/27658390
http://dx.doi.org/10.4143/crt.2016.292