A dynamic pathway analysis approach reveals a limiting futile cycle in N-acetylglucosamine overproducing Bacillus subtilis

Recent advances in genome engineering have further widened the gap between our ability to implement essentially any genetic change and understanding the impact of these changes on cellular function. We lack efficient methods to diagnose limiting steps in engineered pathways. Here, we develop a gener...

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Detalles Bibliográficos
Autores principales: Liu, Yanfeng, Link, Hannes, Liu, Long, Du, Guocheng, Chen, Jian, Sauer, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512609/
https://www.ncbi.nlm.nih.gov/pubmed/27324299
http://dx.doi.org/10.1038/ncomms11933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512609/
https://www.ncbi.nlm.nih.gov/pubmed/27324299
http://dx.doi.org/10.1038/ncomms11933

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