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Sex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator

Male gender is protective against multiple sclerosis and other T-cell-mediated autoimmune diseases. This protection may be due, in part, to higher androgen levels in males. Androgen binds to the androgen receptor (AR) to regulate gene expression, but how androgen protects against autoimmunity is not...

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Detalles Bibliográficos
Autores principales: Zhu, Meng-Lei, Bakhru, Pearl, Conley, Bridget, Nelson, Jennifer S., Free, Meghan, Martin, Aaron, Starmer, Joshua, Wilson, Elizabeth M., Su, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512610/
https://www.ncbi.nlm.nih.gov/pubmed/27072778
http://dx.doi.org/10.1038/ncomms11350