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Genetic lineage tracing defines myofibroblast origin and function in the injured heart

Cardiac fibroblasts convert to myofibroblasts with injury to mediate healing after acute myocardial infarction (MI) and to mediate long-standing fibrosis with chronic disease. Myofibroblasts remain a poorly defined cell type in terms of their origins and functional effects in vivo. Here we generate...

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Detalles Bibliográficos
Autores principales: Kanisicak, Onur, Khalil, Hadi, Ivey, Malina J., Karch, Jason, Maliken, Bryan D., Correll, Robert N., Brody, Matthew J., J. Lin, Suh-Chin, Aronow, Bruce J., Tallquist, Michelle D., Molkentin, Jeffery D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512625/
https://www.ncbi.nlm.nih.gov/pubmed/27447449
http://dx.doi.org/10.1038/ncomms12260