A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours

Salmonella enterica serotype Typhimurium is a food-borne pathogen that also selectively grows in tumours and functionally decreases P-glycoprotein (P-gp), a multidrug resistance transporter. Here we report that the Salmonella type III secretion effector, SipA, is responsible for P-gp modulation thro...

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Detalles Bibliográficos
Autores principales: Mercado-Lubo, Regino, Zhang, Yuanwei, Zhao, Liang, Rossi, Kyle, Wu, Xiang, Zou, Yekui, Castillo, Antonio, Leonard, Jack, Bortell, Rita, Greiner, Dale L., Shultz, Leonard D., Han, Gang, McCormick, Beth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512628/
https://www.ncbi.nlm.nih.gov/pubmed/27452236
http://dx.doi.org/10.1038/ncomms12225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512628/
https://www.ncbi.nlm.nih.gov/pubmed/27452236
http://dx.doi.org/10.1038/ncomms12225

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