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A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours
Salmonella enterica serotype Typhimurium is a food-borne pathogen that also selectively grows in tumours and functionally decreases P-glycoprotein (P-gp), a multidrug resistance transporter. Here we report that the Salmonella type III secretion effector, SipA, is responsible for P-gp modulation thro...
Autores principales: | Mercado-Lubo, Regino, Zhang, Yuanwei, Zhao, Liang, Rossi, Kyle, Wu, Xiang, Zou, Yekui, Castillo, Antonio, Leonard, Jack, Bortell, Rita, Greiner, Dale L., Shultz, Leonard D., Han, Gang, McCormick, Beth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512628/ https://www.ncbi.nlm.nih.gov/pubmed/27452236 http://dx.doi.org/10.1038/ncomms12225 |
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