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Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion

BACKGROUND: Clonal competition in cancer describes the process in which the progeny of a cell clone supersedes or succumbs to other competing clones due to differences in their functional characteristics, mostly based on subsequently acquired mutations. Even though the patterns of those mutations ar...

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Detalles Bibliográficos
Autores principales: Cornils, Kerstin, Thielecke, Lars, Winkelmann, Doreen, Aranyossy, Tim, Lesche, Mathias, Dahl, Andreas, Roeder, Ingo, Fehse, Boris, Glauche, Ingmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512731/
https://www.ncbi.nlm.nih.gov/pubmed/28709463
http://dx.doi.org/10.1186/s12943-017-0668-x