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Endocannabinoid receptor blockade reduces alanine aminotransferase in polycystic ovary syndrome independent of weight loss

BACKGROUND: Evidence suggests that endocannabinoid system activation through the cannabinoid receptor 1 (CB1) is associated with enhanced liver injury, and CB1 antagonism may be beneficial. The aim of this study was to determine the impact of rimonabant (CB1 antagonist) on alanine aminotransferase (...

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Detalles Bibliográficos
Autores principales: Dawson, Alison J., Kilpatrick, Eric S., Coady, Anne-Marie, Elshewehy, Abeer M. M., Dakroury, Youssra, Ahmed, Lina, Atkin, Stephen L., Sathyapalan, Thozhukat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512818/
https://www.ncbi.nlm.nih.gov/pubmed/28705172
http://dx.doi.org/10.1186/s12902-017-0194-2