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STAT1-dependent and -independent pulmonary allergic and fibrogenic responses in mice after exposure to tangled versus rod-like multi-walled carbon nanotubes

BACKGROUND: Pulmonary toxicity of multi-walled carbon nanotubes (MWCNTs) is influenced by physicochemical characteristics and genetic susceptibility. We hypothesized that contrasting rigidities of tangled (t) versus rod-like (r) MWCNTs would result in differing immunologic or fibrogenic responses in...

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Detalles Bibliográficos
Autores principales: Duke, Katherine S., Taylor-Just, Alexia J., Ihrie, Mark D., Shipkowski, Kelly A., Thompson, Elizabeth A., Dandley, Erinn C., Parsons, Gregory N., Bonner, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512939/
https://www.ncbi.nlm.nih.gov/pubmed/28716119
http://dx.doi.org/10.1186/s12989-017-0207-3