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Short DNA sequence patterns accurately identify broadly active human enhancers
BACKGROUND: Enhancers are DNA regulatory elements that influence gene expression. There is substantial diversity in enhancers’ activity patterns: some enhancers drive expression in a single cellular context, while others are active across many. Sequence characteristics, such as transcription factor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512948/ https://www.ncbi.nlm.nih.gov/pubmed/28716036 http://dx.doi.org/10.1186/s12864-017-3934-9 |