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Short DNA sequence patterns accurately identify broadly active human enhancers

BACKGROUND: Enhancers are DNA regulatory elements that influence gene expression. There is substantial diversity in enhancers’ activity patterns: some enhancers drive expression in a single cellular context, while others are active across many. Sequence characteristics, such as transcription factor...

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Detalles Bibliográficos
Autores principales:	Colbran, Laura L., Chen, Ling, Capra, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512948/ https://www.ncbi.nlm.nih.gov/pubmed/28716036 http://dx.doi.org/10.1186/s12864-017-3934-9

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