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Use of haplotypes to identify regions harbouring lethal recessive variants in pigs
BACKGROUND: Lethal recessive genetic variants are maintained at relatively low frequencies in a population in the heterozygous state, but by definition are fatal and therefore unobserved in the homozygous state. Since haplotypes allow the tagging of rare and untyped genetic variants, they have poten...
Autores principales: | Howard, David M., Pong-Wong, Ricardo, Knap, Pieter W., Woolliams, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512953/ https://www.ncbi.nlm.nih.gov/pubmed/28709397 http://dx.doi.org/10.1186/s12711-017-0332-3 |
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